Last fall, I started on 2000 mg sulfasalazine. where the heck do you buy this stuff on alldaychemist? Major hair loss started a few months after - I mean, major. I don't fancy getting chronic diarrhoea or vomiting either. Switched to Sulfasalazine and the hair loss stopped, but in the last couple months started losing hair again and have a bald patch on the back of my head. Subject: Re: Sulfasalazine OR Methotrexate? Docs didnât believe it was sulfa, just stress. A deficiency in folic acid can cause thinning and loss of hair. Promising results have been published in the past with the use of sulfasalazine in alopecia areata. Iâve never experienced anything like this, am relatively young, ethnic so have lots of hair to come out (and oh it did). how much did 3 months supply cost you? Sulfasalazine can have an affect on folic acid levels causing a deficiency. Alopecia areata is an unpredictable, autoimmune, hair loss disease affecting about 2% of the population. typed in Sulfasalazine didn't show up. There are several existing treatments for alopecia areata but none of them offers stable and satisfactory results. Oh yes hair loss, I was worried about that one too, to be honest all the possible side effects sound pretty unpleasant, even if not hugely serious (like lung damage which does seem to be fairly rare). Switched to Sulfasalazine 7 months ago on 2000mg. Hair Loss Study Abstract Sulfasalazine is used as a therapy for various autoimmune conditions, including psoriasis; its effectiveness is presumed to be the result of its immunomodulatory effects. Forced to stop Methotrexate at week 8 due to hair loss. 3 ⦠Alopecia areata is an autoimmune disease mediated by T lymphocytes that results in patchy or confluent hair loss involving the scalp and body. Indirectly, the answer is yes. Sulfasalazine for Alopecia Areata. I was told it was the PsA. I'm 25 and this is NOT a side effect of sulfasalazine, so I guess this is just what many uc sufferers have to ⦠1 The pathologic process involves a perifollicular T-cell infiltrate that causes a cytokine-mediated premature conversion of affected hairs from anagen to telogen 2 and abnormal keratinization with resultant abnormalities of the hair shaft. People with rheumatoid arthritis (RA) may experience hair loss as a symptom of the disease or due to medication that they are taking. Sulfasalazine oral tablet is a prescription medication that's used to treat rheumatoid arthritis, juvenile rheumatoid arthritis, and ulcerative colitis. 4 months on 2000mg per day but no improvement but also no side effects. Reduced me to 1000 mg nonetheless. 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